Macromolecular Crystallography

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Instructor: Loren Williams, Office; IBB, Office Phone; 4-9752, Lab phone; 4-8338, email: (Please put "CHEM 6581, lastname" in the subject line.)

Text: Outline of Crystallography for Biologists, David Blow, Oxford University Press 2002, online version

Crystallography Web Material: Tools | Resources

Class Time/Place: 11:00 am - 12:00 pm, MWF, MS&E 1222

Grades: based on six quizes, class participation, and a project.

Section 1: X-rays, X-ray Sources and Detectors

Section 2: Crystals and Symmetry

Section 3: Waves

Section 4: Diffraction

Section 5: Diffraction by Crystals

Section 6: Intensity Measurements

Section 7: Isomorphous Replacement

Section 8: Anomalous Scattering

Section 9: Molecular Replacement

Section 10: Density Modification

Section 11: Maps

Section 12: Refinement

Section 13: Accuracy

Section 14: Structural Analysis

Section 15: Visualization