| 69. Richardson, J. S., Schneider, B., Murray, L. W., Kapral, G. J., Immormino, R. M., Headd, J. J., Richardson, D. C., Ham, D., Hershkovits, E., Williams, L. D., Keating, K. S., Pyle, A. M., Micallef, D., Westbrook, J., and Berman, H. M. "RNA backbone: Consensus all-angle conformers and modular string nomenclature", RNA, 14, 1-17 (2008) (pdf). | |||||||||||
| 68. Watkins, D., Hsiao, C., Woods, K. K., Koudelka, G. B., and Williams, L. D. "P22 c2 Repressor-Operator Complex: Mechanisms of Direct and Indirect Readout" Biochemistry, 47, 2325-2338 (2008) (pdf). | |||||||||||
| 67. Gold, B., Marky, L.M., Stone, M.P. and Williams, L. D., "A Review of the Role of the Sequence-Dependent Electrostatic Landscape in DNA Alkylation Patterns", Chem Res Toxicol., 19, 1402-1414 (2006) (pdf). | |||||||||||
| 66. Komeda, S., Moulae, T., Woods, K. K., Chikuma, M., Farrell, N. P., Williams, L. D., "A Third Mode of DNA Binding: Phosphate Clamps by a Polynuclear Platinum Complex", J. Am. Chem. Soc. 128, 16092-16103, (2006) (pdf). |
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| 65. Hsiao, C., Mohan, S., Hershkovitz, E., Tannenbaum, A., Williams, L. D., "Single Nucleotide RNA Choreography", Nucleic Acids Res. 34, 1481-1491 (2006) (pdf). |
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63. Hershkowitz, E., Sapiro, G., Tannenbaum, A. and Williams, L. D., "Statistical Analysis of the RNA Backbone", IEEE/ACM Transactions on Computational Biology and Bioinformatics, 3, 33-46 (2006) (pdf). |
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| 62. Moulaei, T., Maehigashi, T., Lountos, G., Komeda, S., Watkins, D., Stone, M. P., Marky, L., Li, J.-S., Gold, B. and Williams, L. D., "Structure of B-DNA with Cations Tethered in the Major Groove", Biochemistry, 44, 7458-7468, (2005) (pdf). |
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| 61. Williams, L. D. "Between Objectivity and Whim: Nucleic Acid Structural Biology", in Topics in Current Chemistry, (Chaires, J. B. & Waring, M., eds.) 77-88 (2005). |
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| 60. Woods, K. K., Maehigashi, T., Howerton, S. B., Sines, C. C., Tannenbaum, S. and Williams, L. D., "High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2", J. Am. Chem. Soc., 126, 15330-15331 (2004) (pdf). |
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| 59. Hershkovitz, E., Tannenbaum, E., Howerton, S. B., Sheth, A., Tannenbaum, A., and Williams, L. D., "Automated Identification of RNA Conformational Motifs: Theory and application to the HM LSU 23S rRNA", Nucleic Acids Res. 31, 6249-6257 (2003) (pdf). |
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| 58. Razskazovskiy, Y., Debije, M. G., Howerton, S. B., Williams, L. D. and Bernhard, W., "Strand Breaks in X-Irradiated Crystalline DNA: Alternating CG Oligomers", Radiation Research, 160, 334-339 (2003) (pdf). |
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| 57. Howerton, S. B., Nagpal, A., and Williams, L. D., "Surprising Roles for Electrostatic Interactions in DNA-Ligand Complexes", Biopolymers, 69, 87-99 (2003) (pdf). | |
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| 56. Reynisson, J., Schuster, G. B., Howerton, S.B., Williams, L. D., Barnett, R. N., Cleveland, C. L., Landman, U., Harrit, N. and Chaires, J. B., "The Intercalation of Trioxatriangulenium Ion (TOTA+) in DNA: Binding, Electron Transfer, X-Ray Crystallography, and Electronic Structure", J. Am. Chem. Soc., 125, 2072-2083 (2003) (pdf). |
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| 55. Woods, K., Lan, T., McLaughlin, L. W. and Williams, L. D., "The Role of Minor Groove Functional Groups in DNA Hydration", Nucleic Acids Research, 31, 1536-1540 (2003) (pdf). |
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| 54. Hamelberg, D., Williams, L. D. and Wilson, W. D., "The Effect of Neutralized Phosphate Backbone on the Minor Groove Structure of B-DNA", Nucleic Acids Research, 30, 3615-3623 (2002) (pdf). |
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| 53. Hamelberg, D., Williams, L. D. and Wilson, W. D., "Influence of the Dynamic Positions of Cations on the Structure of the DNA Minor Groove: Sequence-Dependent Effects", J. Am. Chem. Soc., 123, 7745-7755 (2001) (pdf). | |||||||||||
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| 52. Howerton, S. B., Sines, C. C., VanDerveer, D. and Williams, L. D., "Locating Monovalent Cations in the Grooves of B-DNA", Biochemistry, 40, 10023-10031 (2001) (pdf). | |||||||||||
| 51. Peek, M. E. and Williams, L. D., "X-Ray Crystallography of DNA-Drug Complexes", Methods in Enzymology, 340, 282-290 (2001) (pdf). |
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| 50. Sines, C. C., McFail-Isom, L., Howerton, S. B., VanDerveer, D. and Williams, L. D., "Cations mediate B-DNA conformational heterogeneity", J. Am. Chem. Soc., 122, 11048-11056 (2000) (pdf). | |||||||||||
| 49. Hamelberg, D., McFail-Isom, L., Williams, L. D. and Wilson, W. D., "The Flexible Structure of DNA: Ion Dependence of Minor-Groove Structure and Dynamics", J. Am. Chem. Soc., 122, 110513-10520 (2000) (pdf). | |||||||||||
| 48. Williams, L. D. and Maher, L. J., "Electrostatic Mechanisms of DNA Deformation", Annual Review of Biophysics and Biomolecular Structure, 29, 497-521 (2000) (pdf). | |||||||||||
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| 47. Woods, K.K., McFail-Isom, L., Sines, C. C., Howerton, S. B. and Williams, L. D., "Delocalized Monovalent Cations Sequester within the AT-Tract Minor Groove of [d(CGCGAATTCGCG)]2", J. Am. Chem. Soc., 122, 1546-1547 (2000) (pdf). | |||||||||||
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| 46. Shui, X., Peek, M. E., Lipscomb, L. A., Gao, Q., Ogata, C., Roquest, B. P., Garbay-Jaureguiberry, C. and Williams, L. D., " Effects of Cationic Charge on Three-Dimensional Structures of Intercalative Complexes: Structure of a bis-Intercalated DNA Complex Solved by MAD Phasing", Current Medicinal Chemistry, 7, 59-71 (2000) (pdf). | |||||||||||
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| 45. McFail-Isom, L., Sines, C. and Williams, L. D., "DNA Structure: Cations in Control?", Current Opinion in Structural Biology, 9, 298-304 (1999) (pdf). | |||||||||||
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| 44. Zhang, Y., Kotliar, A. M., Kumar, S. and Williams, L. D., "Fibers from Soybean Protein and Poly(vinyl alcohol)", Journal of Applied Polymer Science, 71, 11-19 (1999) (abstract in html). | |||||||||||
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| 43. Gasper, S. M., Armitage, B., Shui, X., Hu, G. G., Yu, C., Schuster, G.B. and Williams, L. D., "Structure of a Photochemical Cleavage Agent Bound to DNA", J. Am. Chem. Soc., 48, 12402-12409 (1998) (pdf). | |||||||||||
| 42. McFail-Isom, L., Shui, X. and Williams, L. D., "Divalent Cations Stabilize Unstacked Conformations of DNA and RNA by Interacting with Base P Systems", Biochemistry, 37, 17105-17111 (1998) (pdf). | |||||||||||
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| 41. Shui, X., McFail-Isom, L., Sines, C., VanDerveer, D. and Williams, L. D., "Structure of the Potassium Form of CGCGAATTCGCG: DNA Deformation by Electrostatic Collapse around Small Cations", Biochemistry, 37, 16877-16887 (1998) (pdf). | |||||||||||
40. Shui, X., McFail-Isom, L., Hu, G. G. and Williams, L. D., "The B-DNA Dodecamer at High Resolution reveals a Spine of Water on Sodium", Biochemistry, 37, 8541-8555 (1998) (article in pdf).
38. Milano, M. T., Hu, G. G., Williams, L. D. and Bernhard, W. A., "Migration of Electrons and Holes in Crystalline d(CGATCG)-anthracycline Complexes X-Irradiated at 4K", Radiation Research, 150, 101-114 (1998) (abstract in html).
37. Davis, T. M., McFail-Isom, L., Keane, E. and Williams, L. D., "UV Spectroscopy Fails to Detect a DNA Hairpin to Coil Transition", Biochemistry, 37, 6975-6978 (1998) (article in pdf).
36. Breslin, D. T., Coury, J. E., Anderson, J. R., McFail-Isom, L., Kan, Y., Williams, L. D., Bottomley, L. A. and Schuster, G. B., "Anthraquinone Photonuclease Structure Determines its Mode of Binding to DNA and the Cleavage Chemistry Observed", J. Am. Chem. Soc., 119, 5043-5044 (1997) (article in pdf).
35. Hu, G.G., Shui, X., Leng, F., Preibe, W., Chaires, J. B. and Williams, L. D., "Structure of a DNA-Bisdaunmycin Complex", Biochemistry, accelerated publication, 36, 5940-5946 (1997) (pdf).
34. Coury, J. E., Anderson, J. R., McFail-Isom, L., Williams, L. D. and Bottomley, L. D., "Scanning Force Microscopy of Small Ligand-Nucleic Acid Complexes: Tris(o-phenanthroline)ruthenium(II) as a Test for a New Assay", J. Am. Chem. Soc., 119, 3792-3796, (1997) (article in pdf).
33. Coury, J. E., McFail-Isom, L., Williams, L. D. and Bottomley, L. D., "A Novel Application of Scanning Force Microscopy: Assay for Mode of Binding of 2.5-Bis(4-amidinopheny)furan) to DNA", Proc. Natl. Acad. Sci., USA, 93, 12283-12286 (1996) (abstract in html).
32. Gao, Q., Sood, A., Shaw, B. R. and Williams, L. D., "3-Cyanoborane-Cytidine", Acta Cryst., C52, 1823-1825 (1996).
31. Lipscomb, L. A., Zhou, F. X., Presnell, S. R., Woo, R. J., Peek, M. E., Plaskon, R. R. and Williams, L. D., "Structure of a DNA-Porphyrin Complex", Biochemistry accelerated publication, 35, 2818-2823 (1996) (pdf).
30. Lipscomb, L. A., Zhou, F. X. and Williams, L. D., "Clathrate Hydrates are Poor Models for Biomolecule Hydration", Bioploymers, 38, 177-181 (1996) (abstract in html).
29. Bertrand, J. A., Oleksyszyn, J., Kam, C.-H., Boduszek, B., Presnell, S., Plaskon, R. R., Suddath, F. L., Powers, J. C. and Williams, L. D., "Inhibition of Trypsin and Thrombin by Amino(4-amidinophenyl)methanephosphonate Diphenyl Ester Derivatives: X-ray Structures and Molecular Models", Biochemistry, 35, 3147-3155 (1996) (pdf).
28. Coury, J. E., McFail-Isom, L., Presnell, S., Williams, L. D. and Bottomley, L. D., "Scanning Probe Visualization of Electrostatically Immobilized Intercalating Drug-DNA Complexes", J. Vac. Sci. and Technol., 13, 1746-1751 (1995).
27. Lipscomb, L. A., Peek, M. E., Morningstar, M. L., Verghis, S. M., Miller, E. M., Rich, A., Essigmann, J. M. and Williams, L. D., "X-ray Structure of a DNA Decamer Containing 7,8-Dihydro-8-oxoguanine", Proc. Natl. Acad. Sci. USA, 92, 719-723 (1995) (abstract).
26. Peek, M. E., Lipscomb, L. A., Haseltine, J., Gao, Q., Roques, B. P., Garbay-Jaureguiberry, C. and Williams, L. D., "Asymmetry and Dynamics in Bis-Intercalated DNA", J. Bioorg. and Med. Chem., 3, 693-699 (1995) (abstract).
25. Lipscomb, L. A., Peek, M. E., Zhou, F. X., Bertrand, J. A., VanDerveer, D. and Williams, L. D., "Water Ring Structure at DNA Interfaces: Hydration and Dynamics of DNA-Anthracycline Complexes", Biochemistry, 33, 3649-3659 (1994) (abstract).
24. Peek, M. E., Lipscomb, L. A., Bertrand, J. A., Gao, Q., Roques, B. P., Garbay-Jaureguiberry, C. and Williams, L. D., "DNA Distortion in bis-Intercalated Complexes", Biochemistry, accelerated publication, 33, 3794-3800 (1994) (abstract).
23. Bancroft, D., Williams, L. D., Rich, A. and Egli, M., "The Low Temperature Crystal Structure of the Pure-Spermine Forms of Z-DNA Reveals Binding of a Spermine Molecule in the Minor Groove", Biochemistry, 33, 1073-1086 (1994) (abstract).
22. MacPhail, R. A., Williams, L. D., Jones, D. A. and Shaw, B. R., "Variable Temperature Infrared Spectroscopy of Cytosine-Guanine Base Pairs: Tautomerism versus Polarization", J. Biomol. Struct. Dynam., 9, 881-898 (1992).
21. Williams, L. D. and Gao, Q., "DNA-Ditercalinium Interactions: Implications for Recognition of Damaged DNA", Biochemistry, 31, 4315-4324 (1992) (abstract).
20. Gao, Q., Williams, L. D., Egli, M., Rabinovich, D., Chen, S.-H., Quigley, G. J. and Rich, A., "Drug Induced DNA Repair: X-Ray Structure of a DNA-Ditercalinium Complex", Proc. Natl. Acad. Sci. USA, 88, 2422-2426 (1991).
19. Egli, M., Williams, L. D., Frederick, C. A. and Rich, A., "DNA-Nogalamycin Interactions", Biochemistry, 30, 1364-1372 (1991) (pdf).
18. Egli, M., Williams, L. D., Gao, Q. and Rich, A., "Structure of the Pure-Spermine Form of Z-DNA (Magnesium Free) at 1A Resolution", Biochemistry, 30, 11388-11402 (1991) (pdf).
17. Feuerstein, B. G., Williams, L. D., Basu, H. S. and Marton, L. J., "Implications and Concepts of Polyamine-Nucleic Acid Interactions", J. Cell. Biochemistry, 46, 37-47 (1991).
16. Frederick, C. A., Williams, L. D., Ughetto, G., van der Marel, G. A., van Boom, J. H., Rich, A. and Wang, A. H.-J., "Structural Comparison of Anti-Cancer Drug-DNA Complexes: Adriamycin and Daunomycin", Biochemistry, 29, 2538-2549 (1990) (pdf).
15. Egli, M., Gessner, R. V., Williams, L. D., Quigley, G. J., van der Marel, G. A., van Boom, J. H., Rich, A. and Frederick, C. A., "Atomic Resolution Structure of the Cellulose-Synthase Regulator Cyclic Ribo-Diguanylic Acid", Proc. Natl. Acad. Sci. USA, 87, 3235-3239 (1990).
14. Williams, L. D., Egli, M., Ughetto, G., van der Marel, G. A., van Boom, J. H., Quigley, G. J., Wang, A. H.-J., Rich, A. and Frederick, C. A., "Structure of 11-Deoxydaunomycin Bound to DNA Containing a Phosphorothioate", J. Mol. Biol., 215, 313-320 (1990).
13. Williams, L. D., Frederick, C. A., Ughetto, G. and Rich, A., "Ternary Interactions of Spermine with DNA:4'-Epiadriamycin and other DNA:Anthracycline Complexes", Nucleic Acids Res., 18, 5533-5541 (1990).
12. Williams, L. D., Williams, N. G. and Shaw, B. R., "In a Model C:G Base Pair: One Amino Group Rotates and the Other Does Not", J. Am. Chem. Soc., 112, 829-833 (1990). (pdf)
11. McCarthy, J. G., Williams, L. D. and Rich, A., "Chemical Reactivity of Potassium Permangenate and Diethyl Pyrocarbonate with B DNA: Specific Reactivity with Short A-Tracts", Biochemistry, 29, 6071-6081 (1990) (pdf).
10. Williams, L. D., Egli, M., Gao, Q., Bash, P., van der Marel, G. A., van Boom, J. H., Rich, A. and Frederick, C. A., "Structure of Nogalamycin Bound to a DNA Hexamer", Proc. Natl. Acad. Sci. USA, 87, 2225-2229 (1990).
9. Williams, N. G., Williams, L. D. and Shaw, B. R., "Dimers, Trimers and Tetramers of Cytosine with Guanine", J. Am. Chem. Soc., 111, 7205-7209 (1989). (pdf)
8. Williams, L. D. and Goldberg, I. H., "Selective Strand Scission by Intercalating Drugs at DNA Bulges", Biochemistry, 27, 3004-3011 (1988). (pdf)
7. Williams, L. D., Thivierge, J. and Goldberg, I. H., "Specific Binding of o-Phenanthroline at a DNA Structural Lesion", Nucleic Acids Research, 16, 11607-11615 (1988).
6. Williams, L. D., Chawla, B. and Shaw, B. R., "The Hydrogen Bonding of Cytosine with Guanine: Calorimetric and 1H-NMR Analysis of the Molecular Interactions of Nucleic Acid Bases", Biopolymers, 26, 591-603 (1987).
5. Williams, L. D. and Shaw, B. R., "Protonated Base Pairs Explain the Ambiguous Pairing Properties of O6-Methylguanine", Proc. Natl. Acad. Sci. USA, 84, 1779-1783 (1987).
4. Aartsma, T., Gouterman, M., Jochum, C., Kwiram, A., Pepich, B. and Williams, L. D., "Porphyrins 43. Triplet Sublevel Emission of Platinum Tetrabenzoporphyrin by Spectrothermal Principal Component Decomposition", J. Am. Chem. Soc., 104, 6278-6283 (1982).
Publications (book chapters):
3. Williams, L. D. and Rich, A. "Understanding DNA Interactions and Deformations from 3-Dimensional Structures", in Molecular Structure and Life, (Kyogoku, Y. & Nishimura, N., eds.) 3-27 (1992).
2. Williams, L. D., Egli, M., Gao, Q. and Rich, A. "DNA Intercalation: Helix Unwinding and Neighbor Exclusion", in Structure & Function, Volume I: Nucleic Acids, (Sarma, R. H. & Sarma, M. H., eds.) 107-125 (1992).
1. Williams, L. D., Frederick, C. A., Gessner, R. V. and Rich, A. "Molecular Structures of Spermine: Nucleic Acid Complexes", in Molecular Conformation and Biological Interactions, (Balaram, P. & Ramaseshan, S., eds.) 295-309 (1991).