Web: For this course you will use the:
structure teaching tool|rasmol and pdb tutorial|williams page|ikeda page|links page|

Description: This course covers principles of protein, nucleic acid, carbohydate and membrane structure, stability and dynamics. Topics will include forces that determine and stabilize 3-dimensional structures of biological molecules, and detailed descriptions of 3-D structures. The course will contain brief introductions to the methods by which this information is obtained.

Instructors:

Dr. Loren Williams, Office; B-18 Boggs Building, Lab; B78/79 Boggs Building, Office Phone; (404) 894-9752, Lab phone; (404) 894-8338, email; loren.williams@chemistry.gatech.edu.

Dr. Rick Ikeda, Office; 2-15 Boggs Building, Lab; 2-10 Boggs Building, Office Phone; (404) 894-4037, Lab phone; (404) 894-2186, email; rick.ikeda@chemistry.gatech.edu.

Email: All required email must be addressed to Dr. Loren Williams at the address above. The subject line must contain the course number and the student name, with the following syntax: "CHEM 4511, Jim Powers".

Class Time and Place: 9:35-10:55am; Tues, Thurs; Room 17 College of Computing.

TA: Elaine Keane; gt4246a@prism.gatech.edu

Textbook: This course will cover primarily the first 14 chapters of Voet and Voet, Biochemistry, second edition, 1995, John Wiley and Sons.

Grades: Grades will be based on three midterms (22% each), class participation (20%), and a final quiz (14%). The class participation portion of the grade will be determined by peformance on class assignments and discussions. Exams will cover (1) the assigned reading, (2) classroom discussions, and (3) material posted on the course homepage.

Absences: Lack of attendence or tardy assignments will be excused only with written documentation. No exceptions will be made to this rule.

Graduating Seniors: Graduating seniors must identify themselve within the first two weeks of the quarter.

Honor Code: Students are expected to follow the Georgia Tech Academic Honor Code.

Exams: Exams are scheduled on 4/8, 4/27, 5/8 and 6/9 (final). The final exam will be cumulative, but will focus primarily on the later part of the course.

Rasmol Tutorial. The rasmol and pdb tutorial must be handed in on 4/15, by email. The email subject line must contain the following; "CHEM 4511, Jim Powers, rasmol". Substitute your name for Jim Powers.

Audit. To earn a satisfactory audit one must attend all classes, read all assignments, and participate in class discussions.

Schedule

Week	Date	Voet/Voet Chapter	Subject	Note
1	3/30, 4/1	1-3	Intro/Background
2	4/6, 4/8	4	Amino Acids	Exam 4/8
3	4/13, 4/15	6	Covalent Structure (proteins)	Rasmol tutorial due 4/15
4	4/20, 4/22	7	3D structures (proteins)
5	4/27, 4/29	28.1-28.5 30.1-30.2B	3D structures (nucleic acids)	Exam 4/27
6	5/4, 5/6	28.6A, 29.3D, 30.2C, 30.3A	3D structures (protein-nucleic acid complexes)
7	5/11, 5/13	8, 9	Protein Folding, Hemoglobin
8	5/18, 5/20	12, 13	Enzymes (rates)	Exam 5/18
9	5/25, 5/27	14	Enzymes (mechanisms)
10	6/1, 6/3	10, 11	Sugars and Polysaccharides Lipids and Membranes	Final quiz 6/3

williams ikeda quirk