************************************************************************** From: Phil Grace Date: Tue, 28 Oct 1997 16:44:23 -0000 Subject: GC-MS of TMS Sugars Organization: King's College London I was wondering if anyone out there could recommend a good reference on the GC-MS analysis of the trimethylsilyl derivatives of monosaccharides. I have read D.C. DeJongh et al., J. Am. Chem. Soc., 91, 1728 (1969) which has been extensively cited in the literature but was wondering if any more recent reviews in this area had been published as my literature search has only come up with rather specific applications of this technique whereas I was looking for a more general review or study of the area using modern GC-MS instrumentation. Any recommendations for reading in this area would be very gratefully received. Thanks in advance, Phil Grace phil.grace@kcl.ac.uk King's College London ****************************************************************************** From: Leonore Blok-Tip Date: Tue, 4 Nov 1997 16:37:41 +0100 Subject: GC-MS of TMS Sugars Organization: * Dear Phil, GC-MS of TMS sugars is a rather common method, used for a long time already. A book that I find very useful for analysis of carbohydrates is: Analysis of Carbohydrates by GLc and MS, eds, Biermann and McGinnis, C.R.C. Press, Inc., Boca Raton, Fl. 1989. Chapter 4 deals with analysis of TMS sugars. I hope this information is of any help to you. Good luck! Leonore Blok-Tip ------------------------ Dept. Mass Spectrometry Fac. Chemistry Universiteit Utrecht P.O.Box 80083 3508 TB UTRECHT The Netherlands Tel. +31.30.2536793 Fax +31.30.2518219 ------------------------ ****************************************************************************** From: "Little, James L" Date: Sat, 1 Nov 1997 10:55:47 -0500 Subject: Silyl Derivatives of Monosaccharides Organization: * I have not done monosaccharides, but have done a lot of work on understanding silylation reactions. Many side-reactions occur in silylation which are not well documented that can affect quantitative analyses. See my web page noted below: James Little jllittle@eastman.com http://www.preferred.com/~s_little/mspec/index.html Eastman Chemical Company Kingsport, TN 37662 423-229-8685